(2S,4R)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl-2,2,2-d3)pyrrolidine-2-carboxamide O=C(CC1)NC(C1N(C2=O)C(C(C2=C3)=CC=C3N4CCC(CCN5CCNCC5)CC4)=O)=O Site-selective Acetylation

Name: (2S,4R)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl-2,2,2-d3)pyrrolidine-2-carboxamide O=C(CC1)NC(C1N(C2=O)C(C(C2=C3)=CC=C3N4CCC(CCN5CCNCC5)CC4)=O)=O Site-selective Acetylation
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Description

Site-selective Acetylation

Site-specific and hydrophilic ADCs through disulfide-bridged linker and branched PEG

93-101 DOI: 10

1039/C6SC00005C

(2S,4R)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl-2,2,2-d3)pyrrolidine-2-carboxamide O=C(CC1)NC(C1N(C2=O)C(C(C2=C3)=CC=C3N4CCC(CCN5CCNCC5)CC4)=O)=O Site-selective Acetylation

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